British Baker wants you to tell us what the past 12 months have meant for the retail bakery market.We are running our annual Bakery Business Survey over the next few weeks to gauge how 2018 treated businesses that operate shops selling baked goods.Your responses – which will be confidential – will form a key part of our annual Bakery Market Report, to be published this spring.And one lucky reader who completes the survey will win £75-worth of Amazon vouchers.The survey just takes a few minutes to complete and covers topics including sales costs and what the future may hold for the industry.For the first time, we are also looking at retail prices of key take-out baked goods.“In what is proving to be one of the most challenging and tumultuous retail environments, we want to give an accurate picture of how the bakery retail sector is performing, and your views are an essential part of this,” said British Baker editor Vince Bamford.Click here to take part in the Bakery Business Survey.Remember, it takes just minutes to give your answers and, if you complete the survey, you will be entered into our draw to win £75-worth of Amazon vouchers.The closing date for responses is 18 February 2019.
Source:https://www.nibib.nih.gov/news-events/newsroom/injectable-bandage-targets-fatal-internal-bleeding May 22 2018While several products are available to quickly seal surface wounds, rapidly stopping fatal internal bleeding has proven more difficult. Now researchers from the Department of Biomedical Engineering at Texas A&M University are developing an injectable hydrogel bandage that could save lives in emergencies such as penetrating shrapnel wounds on the battlefield.The researchers combined a hydrogel base (a water-swollen polymer) and nanoparticles that interact with the body’s natural blood-clotting mechanism. “The hydrogel expands to rapidly fill puncture wounds and stop blood loss,” explained Akhilesh Gaharwar, Ph.D., assistant professor and senior investigator on the work. “The surface of the nanoparticles attracts blood platelets that become activated and start the natural clotting cascade of the body.”Related StoriesAlternate cell growth pathway could open door to new treatments for metastatic cancersWHO declares the deadly Ebola outbreak in Congo a global health emergencyExciting study shows how centrioles center the process of cell divisionEnhanced clotting when the nanoparticles were added to the hydrogel was confirmed by standard laboratory blood clotting tests. Clotting time was reduced from eight minutes to six minutes when the hydrogel was introduced into the mixture. When nanoparticles were added, clotting time was significantly reduced, to less than three minutes.In addition to the rapid clotting mechanism of the hydrogel composite, the engineers took advantage of special properties of the nanoparticle component. They found they could use the electric charge of the nanoparticles to add growth factors that efficiently adhered to the particles. “Stopping fatal bleeding rapidly was the goal of our work,” said Gaharwar. “However, we found that we could attach growth factors to the nanoparticles. This was an added bonus because the growth factors act to begin the body’s natural wound healing process-;the next step needed after bleeding has stopped.”The researchers were able to attach vascular endothelial growth factor (VEGF) to the nanoparticles. They tested the hydrogel/nanoparticle/VEGF combination in a cell culture test that mimics the wound healing process. The test uses a petri dish with a layer of endothelial cells on the surface that create a solid skin-like sheet. The sheet is then scratched down the center creating a rip or hole in the sheet that resembles a wound.When the hydrogel containing VEGF bound to the nanoparticles was added to the damaged endothelial cell wound, the cells were induced to grow back and fill-in the scratched region-; essentially mimicking the healing of a wound.”Our laboratory experiments have verified the effectiveness of the hydrogel for initiating both blood clotting and wound healing,” said Gaharwar. “We are anxious to begin tests in animals with the hope of testing and eventual use in humans where we believe our formulation has great potential to have a significant impact on saving lives in critical situations.”